One way is using the Stop loss. Second way is not using the stop loss but it is not so simple.
If you don't want to use SL- you need good money managment and big account balance.
For example :
Account balance : 10 000$
Lot size: 5 lot
Numbers of position opened: just 1
In this case you have 2000 pips to hold on floating minus as a defence- so you've elimineted the risk because there is no way that price will go opposit by 2000 pips. It will touch your TP one day- just wait